BDBM786753 2-(7-((2S,5R)-4-(1-(benzo[d]thiazol-6-yl)ethyl)-5-ethyl-2-methylpiperazin-1-yl)-4-methyl-5-oxo-4,5-dihydro-2H-pyrazolo[4,3-b]pyridin-2-yl)acetonitrile::US20250346597, Compound A92a

SMILES CC[C@@H]1CN(c2cc(=O)n(C)c3cn(CC#N)nc23)[C@@H](C)CN1[C@@H](C)c1ccc2ncsc2c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 786753   

TargetDiacylglycerol kinase zeta(Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 786753BDBM786753(2-(7-((2S,5R)-4-(1-(benzo[d]thiazol-6-yl)ethyl)-5-...)
Affinity DataIC50: 9.10nMAssay Description:Enzymatic reactions of DGKζ, DGKα and DGKδ were performed using ADP-Glo assay with lipid micelle substrate. Full length DGK (in-house protein M1-V929...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/4/2026
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 786753BDBM786753(2-(7-((2S,5R)-4-(1-(benzo[d]thiazol-6-yl)ethyl)-5-...)
Affinity DataIC50: 108nMAssay Description:Enzymatic reactions of DGKζ, DGKα and DGKδ were performed using ADP-Glo assay with lipid micelle substrate. Full length DGK (in-house protein M1-V929...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/4/2026
Entry Details
US Patent