BDBM787107 US20250346616, Example 40

SMILES CN1CCN(C[C@@H](C(=O)Nc2cccc3c(-c4cn[nH]c4)c[nH]c23)c2ccccc2)CC1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 787107   

TargetRho-associated protein kinase 2(Human)
Dizal (Jiangsu) Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 787107BDBM787107(US20250346616, Example 40)
Affinity DataIC50: 0.180nMAssay Description:Recombinant ROCK1 and ROCK2 was purchased from Thermo Fisher with catalogue numbers PV3691 and PR71168. The inhibition potency of compounds against t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/5/2026
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Dizal (Jiangsu) Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 787107BDBM787107(US20250346616, Example 40)
Affinity DataIC50: 0.330nMAssay Description:Recombinant ROCK1 and ROCK2 was purchased from Thermo Fisher with catalogue numbers PV3691 and PR71168. The inhibition potency of compounds against t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/5/2026
Entry Details
US Patent