BDBM787215 US12473262, Compound 536

SMILES COc1ccc(C(=O)n2c(-c3cccc4ccccc34)nc3ccc(Cl)cc32)cc1

InChI Key

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 787215   

TargetCytochrome P450 1A2(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787215BDBM787215(US12473262, Compound 536)
Affinity DataIC50: 600nMAssay Description:From 10 mM stock solutions of test compounds, a dilution plate was prepared diluting serially starting from 5 mM up to 2 μM in Acetonitrile/DMSO or M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787215BDBM787215(US12473262, Compound 536)
Affinity DataIC50: 1.70E+3nMAssay Description:From 10 mM stock solutions of test compounds, a dilution plate was prepared diluting serially starting from 5 mM up to 2 μM in Acetonitrile/DMSO or M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787215BDBM787215(US12473262, Compound 536)
Affinity DataIC50: 2.60E+3nMAssay Description:From 10 mM stock solutions of test compounds, a dilution plate was prepared diluting serially starting from 5 mM up to 2 μM in Acetonitrile/DMSO or M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787215BDBM787215(US12473262, Compound 536)
Affinity DataIC50: 4.80E+3nMAssay Description:From 10 mM stock solutions of test compounds, a dilution plate was prepared diluting serially starting from 5 mM up to 2 μM in Acetonitrile/DMSO or M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 2B6(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787215BDBM787215(US12473262, Compound 536)
Affinity DataIC50: 1.60E+4nMAssay Description:From 10 mM stock solutions of test compounds, a dilution plate was prepared diluting serially starting from 5 mM up to 2 μM in Acetonitrile/DMSO or M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787215BDBM787215(US12473262, Compound 536)
Affinity DataIC50: 1.71E+4nMAssay Description:From 10 mM stock solutions of test compounds, a dilution plate was prepared diluting serially starting from 5 mM up to 2 μM in Acetonitrile/DMSO or M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Oregon State University

US Patent
LigandChemical structure of BindingDB Monomer ID 787215BDBM787215(US12473262, Compound 536)
Affinity DataIC50: 5.00E+4nMAssay Description:From 10 mM stock solutions of test compounds, a dilution plate was prepared diluting serially starting from 5 mM up to 2 μM in Acetonitrile/DMSO or M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent