BDBM787317 3-(4-(2,2,2- trifluoroethoxy)phenyl)-2- (trifluoromethyl)- 4H-pyrido[1,2- a]pyrimidin-4-one::US12473289, Example 1-42

SMILES O=c1c(-c2ccc(OCC(F)(F)F)cc2)c(C(F)(F)F)nc2ccccn12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 787317   

TargetAcyl-CoA (8-3)-desaturase(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 787317BDBM787317(3-(4-(2,2,2- trifluoroethoxy)phenyl)-2- (trifluoro...)
Affinity DataIC50: 10.4nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent