BDBM787390 3-(4- (difluoromethoxy)phenyl)-8- methoxy-2-(trifluoromethyl)- 4H-pyrido[1,2-a]pyrimidin- 4-one::US12473289, Example 1-54

SMILES COc1ccn2c(=O)c(-c3ccc(OC(F)F)cc3)c(C(F)(F)F)nc2c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 787390   

TargetAcyl-CoA (8-3)-desaturase(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 787390BDBM787390(3-(4- (difluoromethoxy)phenyl)-8- methoxy-2-(trifl...)
Affinity DataIC50: 6.60nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent