BDBM787398 (4-(8-Methoxy-4-oxo-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-3-yl)phenoxy)acetonitrile::US12473289, Example 21

SMILES COc3ccn2c(=O)c(c1ccc(OCC#N)cc1)c(C(F)(F)F)nc2c3

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 787398   

TargetAcyl-CoA (8-3)-desaturase(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 787398BDBM787398((4-(8-Methoxy-4-oxo-2-(trifluoromethyl)-4H-pyrido[...)
Affinity DataIC50: 5.80nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent