BDBM787494 8-chloro-3-(1- (2,2,3,3,3- pentafluoropropyl)- 1H-pyrazol-4-yl)-2- (trifluoromethyl)-4H- pyrido[1,2- a]pyrimidin-4-one::US12473289, Example 2-6

SMILES O=c1c(-c2cnn(CC(F)(F)C(F)(F)F)c2)c(C(F)(F)F)nc2cc(Cl)ccn12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 787494   

TargetAcyl-CoA (8-3)-desaturase(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 787494BDBM787494(8-chloro-3-(1- (2,2,3,3,3- pentafluoropropyl)- 1H-...)
Affinity DataIC50: 8.20nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent