BDBM788123 7-Methyl-7-azaspiro[3.5]nonan-2-yl (7- fluoro-6-(4-methyl-5,6,7,8-tetrahydro- 1,5-naphthyridin-3-yl)isoquinolin-3- yl)carbamate::US12473301, Compound 133

SMILES Cc1c(-c2cc3cc(NC(=O)OC4CC5(CCN(C)CC5)C4)ncc3cc2F)cnc2c1NCCC2

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 788123   

LigandChemical structure of BindingDB Monomer ID 788123BDBM788123(7-Methyl-7-azaspiro[3.5]nonan-2-yl (7- fluoro-6-(4...)
Affinity DataKi:  1.07nMAssay Description:The following assay concentrations and times were used: 2 nM HPK1, 2 nM Eu-Anti-GST Ab, and 15 nM Tracer222, with 60 min incubation time.III. HPK Lan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent