BDBM789189 US20250353842, Example 33

SMILES CC(C)n1cc(-c2nc(N[C@@H]3CCC[C@H](n4cnc5cncc(C#N)c54)C3)ncc2C#N)cn1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 789189   

TargetCyclin-dependent kinase 12(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 789189BDBM789189(US20250353842, Example 33)
Affinity DataIC50: 50nMAssay Description:Enzyme was pre-incubated with compounds for 30 minutes (CDK1,2,4,6,9) or 60 minutes (CDK7, CDK12, CDK13) prior to addition of ATP and Ulight-peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/10/2026
Entry Details
US Patent