BDBM789240 US20250353842, Example 81

SMILES Cn1cc(-c2cnc3c(c2)ncn3C2CCCC(Nc3ncc(C(F)(F)F)c(-c4cnn(CC(F)F)c4)n3)C2)cn1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 789240   

TargetCyclin-dependent kinase 12(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 789240BDBM789240(US20250353842, Example 81)
Affinity DataIC50: 50nMAssay Description:Enzyme was pre-incubated with compounds for 30 minutes (CDK1,2,4,6,9) or 60 minutes (CDK7, CDK12, CDK13) prior to addition of ATP and Ulight-peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/10/2026
Entry Details
US Patent