BDBM789795 2-(7-((2S,5R)-2,5-diethyl-4-(1-(4-fluoro-2-(trifluoromethyl)phenyl)ethyl)piperazin-1-yl)-4-methyl-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)acetonitrile::US20250353858, Compound A15b

SMILES CC[C@H]1CN([C@@H](C)c2ccc(F)cc2C(F)(F)F)[C@H](CC)CN1c1cc(=O)n(C)c2cc(CC#N)nn12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 789795   

TargetDiacylglycerol kinase zeta(Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 789795BDBM789795(2-(7-((2S,5R)-2,5-diethyl-4-(1-(4-fluoro-2-(triflu...)
Affinity DataIC50: 36nMAssay Description:Enzymatic reactions of DGKζ, DGKα and DGKδ were performed using ADP-Glo assay with lipid micelle substrate. Full length DGKζ in-house protein M1-V929...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 789795BDBM789795(2-(7-((2S,5R)-2,5-diethyl-4-(1-(4-fluoro-2-(triflu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Enzymatic reactions of DGKζ, DGKα and DGKδ were performed using ADP-Glo assay with lipid micelle substrate. Full length DGKζ in-house protein M1-V929...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent