BDBM789915 8-(Cyclohex-1-en-1-yl)-N-(cyclohexylmethyl)-N-methyl-9H-purin-6-amine::US20250353857, Compound TIA03-186

SMILES CN(CC1CCCCC1)c1ncnc2[nH]c(C3=CCCCC3)nc12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 789915   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 789915BDBM789915(8-(Cyclohex-1-en-1-yl)-N-(cyclohexylmethyl)-N-meth...)
Affinity DataIC50: 0.700nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent