BDBM795490 US12570659, Example 85

SMILES CC(C)Nc1c(C(=O)NC2CCN(S(C)(=O)=O)CC2)cnn2cc(-c3ccc(F)nc3)cc12

InChI Key InChIKey=XUGRUWQBIQBGDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 795490   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 795490BDBM795490(US12570659, Example 85)
Affinity DataIC50: 2.5nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substrates (fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 795490BDBM795490(US12570659, Example 85)
Affinity DataIC50: 3.10E+4nMAssay Description:The assay involves using a cell line that expresses the NR1 subunit together with either NR2C or NR2D. These cell lines can be prepared by transfecti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent