BDBM795513 US12570659, Example 109

SMILES CC(C)Nc1c(C(=O)NCCC(C)(C)O)cnn2cc(-c3ccncc3F)nc12

InChI Key InChIKey=IBIYCVOIQSHGJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 795513   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 795513BDBM795513(US12570659, Example 109)
Affinity DataIC50: 12nMAssay Description:The assay involves using a cell line that expresses the NR1 subunit together with either NR2C or NR2D. These cell lines can be prepared by transfecti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 795513BDBM795513(US12570659, Example 109)
Affinity DataIC50: 5.00E+4nMAssay Description:A time resolved FRET-based competition binding assay was used to assess test article binding to JAK3 kinase. His-tagged or GST-tagged kinase at a con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/20/2026
Entry Details
US Patent