BDBM799478 US12583856, Example 100

SMILES N[C@@H]1Cc2ccccc2[C@H]1NC(=O)c1ccc(-c2ccnc3[nH]ccc23)cc1

InChI Key InChIKey=ZCRRNPJALFUFFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 799478   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 799478BDBM799478(US12583856, Example 100)
Affinity DataIC50: 1nMAssay Description:PRKACA assay at Km: In each well of a 384-well plate, 0.007 ng/ul (0.18 nM) of PRKACA enzyme (Millipore: 539482) was incubated in a total of 12.5 μl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent