BDBM800147 Synthesis of (1R,2S)-2-fluoro-N—((S or R)-(6-fluoro-5-isopropylpyridin-2-yl)(1H-indazol-6-yl)methyl)cyclopropane-1-carboxamide ::US20260085034, Compound 3

SMILES CC(C)c1ccc([C@@H](NC(=O)[C@H]2C[C@@H]2F)c2ccc3cn[nH]c3c2)nc1F

InChI Key InChIKey=FTSFOBDKEISACI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 800147   

TargetGlycogen [starch] synthase, muscle(Human)
Maze Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 800147BDBM800147(Synthesis of (1R,2S)-2-fluoro-N—((S or R)-(6-fluor...)
Affinity DataIC50: 55nMAssay Description:Compounds that inhibit the hGYS1 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent