BDBM800170 Synthesis of (R)—N-((2-aminophenyl)(4-isopropylphenyl)methyl)cyclopropanecarboxamide (Compound 64) and (R)—N-(2-(cyclopropanecarboxamido(4-isopropylphenyl)methyl)phenyl)-1-methylazetidine-3-carboxamide ::US20260085034, Compound 26

SMILES CC(C)c1ccc([C@@H](NC(=O)C2CC2)c2ccccc2NC(=O)C2CN(C)C2)cc1

InChI Key InChIKey=SOSIOPXBCKJKFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 800170   

TargetGlycogen [starch] synthase, muscle(Human)
Maze Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 800170BDBM800170(Synthesis of (R)—N-((2-aminophenyl)(4-isopropylphe...)
Affinity DataIC50: 1.19E+3nMAssay Description:Compounds that inhibit the hGYS1 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Maze Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 800170BDBM800170(Synthesis of (R)—N-((2-aminophenyl)(4-isopropylphe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent