BDBM800285 US20260085050, Compound 49

SMILES CC(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCOCC3)cc2)ncc1Br

InChI Key InChIKey=XZKFDACYVYOTSU-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 800285   

TargetALK tyrosine kinase receptor(Human)
Unogen Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 800285BDBM800285(US20260085050, Compound 49)
Affinity DataKd:  4.40nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Unogen Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 800285BDBM800285(US20260085050, Compound 49)
Affinity DataKd:  65nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Unogen Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 800285BDBM800285(US20260085050, Compound 49)
Affinity DataIC50: 917nMAssay Description:EGFR (T790M/C797S/L858R) Kinase Enzyme System from Promega, Cat No. VA7126. ADP-Glo™ Kinase Assay from Promega, Cat No. V6930. The mutant EGFR kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent