BDBM800447 3-(((2-Chloro- [1,1'-biphenyl]- 4- yl)methyl)amino)- N-(3-((6-(2- methoxypyridin- 4-yl)-1H- indazol-4-::3-(((2-Chloro-[1,1'-biphenyl]-4-yl)methyl)amino)-N-(3-((6-(2-methoxypyridin-4-yl)-1H-indazol-4-yl)amino)propyl)propanamide::US20260085062, Example 22

SMILES COc1cc(-c2cc(NCCCNC(=O)CCNCc3ccc(-c4ccccc4)c(Cl)c3)c3cn[nH]c3c2)ccn1

InChI Key InChIKey=MAVMJWISSGASMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 800447   

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800447BDBM800447(3-(((2-Chloro- [1,1'-biphenyl]- 4- yl)methyl)amino...)
Affinity DataIC50: 1.35nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7.5, 200 mM NaCl,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800447BDBM800447(3-(((2-Chloro- [1,1'-biphenyl]- 4- yl)methyl)amino...)
Affinity DataIC50: 1.12E+3nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 μM pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent