BDBM800476 N-(2-(4-(((1- methyl-5- (trifluoromethyl)- 1H-indol-2- yl)methyl)amino) butoxy)ethyl)- 6-(4H-1,2,4- triazol-4-yl)- 1H-indazol-4- amine::N-(2-(4-(((1-methyl-5-(trifluoromethyl)-1H-indol-2-yl)methyl)amino) butoxy)ethyl)-6-(4H-1,2,4-triazol-4-yl)-1H-indazol-4-amine::US20260085062, Example 51

SMILES Cn1c(CNCCCCOCCNc2cc(-n3cnnc3)cc3[nH]ncc23)cc2cc(C(F)(F)F)ccc21

InChI Key InChIKey=FVOLMCPGIIDWLU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 800476   

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800476BDBM800476(N-(2-(4-(((1- methyl-5- (trifluoromethyl)- 1H-indo...)
Affinity DataIC50: 0.710nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7.5, 200 mM NaCl,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800476BDBM800476(N-(2-(4-(((1- methyl-5- (trifluoromethyl)- 1H-indo...)
Affinity DataIC50: 225nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 μM pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent