BDBM800496 3-(((2-chloro-[1,1'-biphenyl]-4-yl)methyl)amino)-N-(3-((6-(3-methyl-4H-1,2,4-triazol-4-yl)-1H-indazol-4-yl)amino)propyl)propanamide::US20260085062, Example 71

SMILES Cc1nncn1-c1cc(NCCCNC(=O)CCNCc2ccc(-c3ccccc3)c(Cl)c2)c2cn[nH]c2c1

InChI Key InChIKey=UBJPQIIMFDTHCD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 800496   

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800496BDBM800496(3-(((2-chloro-[1,1'-biphenyl]-4-yl)methyl)amino)-N...)
Affinity DataIC50: 1.37nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7.5, 200 mM NaCl,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800496BDBM800496(3-(((2-chloro-[1,1'-biphenyl]-4-yl)methyl)amino)-N...)
Affinity DataIC50: 416nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 μM pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent