BDBM800522 6-(isoxazol-4- yl)-N-(2-(4-(((5- (trifluoromethyl)- 1H-indol-2- yl)methyl)amino) butoxy)ethyl)- 1H-indazol-4- amine::6-(isoxazol-4-yl)-N-(2-(4-(((5-(trifluoromethyl)-1H-indol-2-yl)methyl)amino) butoxy)ethyl)-1H-indazol-4-amine::US20260085062, Example 97

SMILES FC(F)(F)c1ccc2[nH]c(CNCCCCOCCNc3cc(-c4cnoc4)cc4[nH]ncc34)cc2c1

InChI Key InChIKey=ORHXUNBOJLDURC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 800522   

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800522BDBM800522(6-(isoxazol-4- yl)-N-(2-(4-(((5- (trifluoromethyl)...)
Affinity DataIC50: 1.42nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7.5, 200 mM NaCl,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800522BDBM800522(6-(isoxazol-4- yl)-N-(2-(4-(((5- (trifluoromethyl)...)
Affinity DataIC50: 104nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 μM pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent