BDBM800543 4-(2-((6-(4H- 1,2,4-triazol-4-yl)-1H- indazol-4-yl)oxy)ethoxy)-N- ((5-cyclobutoxy-1H-indol- 2-yl)methyl)butan-1-amine::4-(2-((6-(4H-1,2,4-triazol-4-yl)-1H-indazol-4-yl)oxy)ethoxy)-N-((5-cyclobutoxy-1H-indol-2-yl)methyl)butan-1-amine::US20260085062, Example 118

SMILES c1cc2[nH]c(CNCCCCOCCOc3cc(-n4cnnc4)cc4[nH]ncc34)cc2cc1OC1CCC1

InChI Key InChIKey=JUHVRIKZQCVMRX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 800543   

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800543BDBM800543(4-(2-((6-(4H- 1,2,4-triazol-4-yl)-1H- indazol-4-yl...)
Affinity DataIC50: 0.860nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7.5, 200 mM NaCl,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800543BDBM800543(4-(2-((6-(4H- 1,2,4-triazol-4-yl)-1H- indazol-4-yl...)
Affinity DataIC50: 1.11E+3nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 μM pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent