BDBM800618 (S)-5-(4-((2-((4-((3-(hydroxymethyl)-5-(trifluoromethoxy)benzyl)amino)pentyl)oxy)ethyl)amino)-1H-indazol-6-yl)pyridazin-3-ol::US20260085062, Example 193

SMILES C[C@@H](CCCOCCNc1cc(-c2cnnc(O)c2)cc2[nH]ncc12)NCc1cc(CO)cc(OC(F)(F)F)c1

InChI Key InChIKey=VPZHIIMGDWROET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 800618   

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800618BDBM800618((S)-5-(4-((2-((4-((3-(hydroxymethyl)-5-(trifluorom...)
Affinity DataIC50: 1.21nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7.5, 200 mM NaCl,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 800618BDBM800618((S)-5-(4-((2-((4-((3-(hydroxymethyl)-5-(trifluorom...)
Affinity DataIC50: 355nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 μM pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent