BDBM800990 US12590070, Compound 1

SMILES CNC(=O)c1cccc(C)c1Nc1nc(Nc2ccc(NC3C4CC5CC3CC(O)(C5)C4)cc2OC)ncc1C(F)(F)F

InChI Key InChIKey=AZAQDTUNRKNDON-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 800990   

TargetFocal adhesion kinase 1(Human)
Samjin Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 800990BDBM800990(US12590070, Compound 1)
Affinity DataIC50: 82.9nMAssay Description:The inhibitory activity of the adamantane derivative compounds of the present invention to FAK, Pyk2 and InsR was confirmed through a biochemical kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
US Patent

TargetProtein-tyrosine kinase 2-beta(Human)
Samjin Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 800990BDBM800990(US12590070, Compound 1)
Affinity DataIC50: 124nMAssay Description:The inhibitory activity of the adamantane derivative compounds of the present invention to FAK, Pyk2 and InsR was confirmed through a biochemical kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
US Patent

TargetInsulin receptor(Human)
Samjin Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 800990BDBM800990(US12590070, Compound 1)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activity of the adamantane derivative compounds of the present invention to FAK, Pyk2 and InsR was confirmed through a biochemical kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
US Patent