BDBM800998 2-((2-((4-((1-(adamantan-2-yl)piperidin-4-yl)oxy)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N,3-dimethylbenzamide ::US12590070, Compound 9

SMILES CNC(=O)c1cccc(C)c1Nc1nc(Nc2ccc(OC3CCN(C4C5CC6CC(C5)CC4C6)CC3)cc2OC)ncc1C(F)(F)F

InChI Key InChIKey=QYVMVXNRPRCXDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 800998   

TargetFocal adhesion kinase 1(Human)
Samjin Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 800998BDBM800998(2-((2-((4-((1-(adamantan-2-yl)piperidin-4-yl)oxy)-...)
Affinity DataIC50: 98.1nMAssay Description:The inhibitory activity of the adamantane derivative compounds of the present invention to FAK, Pyk2 and InsR was confirmed through a biochemical kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
US Patent

TargetInsulin receptor(Human)
Samjin Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 800998BDBM800998(2-((2-((4-((1-(adamantan-2-yl)piperidin-4-yl)oxy)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activity of the adamantane derivative compounds of the present invention to FAK, Pyk2 and InsR was confirmed through a biochemical kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
US Patent