BDBM801002 4-(3-methoxy-4-((4-((2-methyl-6-(methylcarbamoyl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenoxy)-N-methyladamantan-1-carboxamide ::US12590070, Compound 18

SMILES CNC(=O)c1cccc(C)c1Nc1nc(Nc2ccc(OC3C4CC5CC3CC(C(=O)NC)(C5)C4)cc2OC)ncc1C(F)(F)F

InChI Key InChIKey=GVLJBGOLAVCURA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801002   

TargetFocal adhesion kinase 1(Human)
Samjin Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 801002BDBM801002(4-(3-methoxy-4-((4-((2-methyl-6-(methylcarbamoyl)p...)
Affinity DataIC50: 92.9nMAssay Description:The inhibitory activity of the adamantane derivative compounds of the present invention to FAK, Pyk2 and InsR was confirmed through a biochemical kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
US Patent