BDBM801023 2-(((S)-7-((R)-3-cyclohexyl-2-methylpropanoyl)-10-hydroxy-7-azaspiro[4.5]decan-10-yl)methyl)-4-methylisoindolin-1-one::WO2020227365, Compound 4

SMILES Cc1cccc2c1CN(C[C@]1(O)CCN(C(=O)[C@H](C)CC3CCCCC3)CC13CCCC3)C2=O

InChI Key InChIKey=CKEPOXYDMOAEGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801023   

TargetUbiquitin carboxyl-terminal hydrolase 19(Human)
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WIPO
LigandChemical structure of BindingDB Monomer ID 801023BDBM801023(2-(((S)-7-((R)-3-cyclohexyl-2-methylpropanoyl)-10-...)
Affinity DataIC50: 530nMAssay Description:USP19 enzymatic assays were performed in a final volume of 6 μL in buffer containing 20 mM Tris-HCl pH 8.0, (Corning 46-031-CM), and 1 mM GSH (Sigma,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
WIPO WO2020227365