BDBM801039 (R)-4-(4-chlorophenyl)-1-(((S)-7-((R)-3-cyclohexyl-2-methylpropanoyl)-10-hydroxy-7-azaspiro[4.5]decan-10-yl)methyl)pyrrolidin-2-one::WO2020227365, Compound 20

SMILES C[C@H](CC1CCCCC1)C(=O)N1CC[C@@](O)(CN2C[C@@H](c3ccc(Cl)cc3)CC2=O)C2(CCCC2)C1

InChI Key InChIKey=KYTNGDBSGLPDPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801039   

TargetUbiquitin carboxyl-terminal hydrolase 19(Human)
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WIPO
LigandChemical structure of BindingDB Monomer ID 801039BDBM801039((R)-4-(4-chlorophenyl)-1-(((S)-7-((R)-3-cyclohexyl...)
Affinity DataIC50: 110nMAssay Description:USP19 enzymatic assays were performed in a final volume of 6 μL in buffer containing 20 mM Tris-HCl pH 8.0, (Corning 46-031-CM), and 1 mM GSH (Sigma,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
WIPO WO2020227365