BDBM801047 2-(((10S)-10-hydroxy-7-(2-methyl-3-phenylpropanoyl)-7-azaspiro[4.5]decan-10-yl)methyl)-N,N-dimethyl-1-oxoisoindoline-4-carboxamide::WO2020227365, Compound 28

SMILES CC(Cc1ccccc1)C(=O)N1CC[C@@](O)(CN2Cc3c(C(=O)N(C)C)cccc3C2=O)C2(CCCC2)C1

InChI Key InChIKey=SGBSHNNAUHUXHG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801047   

TargetUbiquitin carboxyl-terminal hydrolase 19(Human)
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WIPO
LigandChemical structure of BindingDB Monomer ID 801047BDBM801047(2-(((10S)-10-hydroxy-7-(2-methyl-3-phenylpropanoyl...)
Affinity DataIC50: 3.10E+3nMAssay Description:USP19 enzymatic assays were performed in a final volume of 6 μL in buffer containing 20 mM Tris-HCl pH 8.0, (Corning 46-031-CM), and 1 mM GSH (Sigma,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
WIPO WO2020227365