BDBM801057 N-((1s,4s)-4-(tert-butyl)cyclohexyl)-5-(5- (trifluoromethyl)nicotinamido)-1,2,3- thiadiazole-4-carboxamide::US12590087, Compound 2

SMILES CC(C)(C)[C@H]1CC[C@@H](NC(=O)c2nnsc2NC(=O)c2cncc(C(F)(F)F)c2)CC1

InChI Key InChIKey=ROZYSBLUUFUIQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801057   

TargetUbiquitin carboxyl-terminal hydrolase 36(Human)
Valo Health

US Patent
LigandChemical structure of BindingDB Monomer ID 801057BDBM801057(N-((1s,4s)-4-(tert-butyl)cyclohexyl)-5-(5- (triflu...)
Affinity DataIC50: 329nMAssay Description:USP36 enzymatic assays were performed in a final volume of 6 μL in buffer containing 20 mM Tris-HCl pH 8.0, (Corning 46-031-CM), 3 mM 2-Mercaptoethan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
US Patent