BDBM801062 N-(2,3-dihydro-1H-inden-5-yl)-5-(5- (trifluoromethyl)nicotinamido)-1,2,3- thiadiazole-4-carboxamide::US12590087, Compound 7

SMILES O=C(Nc1snnc1C(=O)Nc1ccc2c(c1)CCC2)c1cncc(C(F)(F)F)c1

InChI Key InChIKey=CWIILOJJCNQWIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801062   

TargetUbiquitin carboxyl-terminal hydrolase 36(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 801062BDBM801062(N-(2,3-dihydro-1H-inden-5-yl)-5-(5- (trifluorometh...)
Affinity DataIC50: 507nMAssay Description:USP36 enzymatic assays were performed in a final volume of 6 μL in buffer containing 20 mM Tris-HCl pH 8.0, (Corning 46-031-CM), 3 mM 2-Mercaptoethan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
US Patent