BDBM801070 5-(5-(trifluoromethyl)nicotinamido)-N-(3- (trifluoromethyl)phenyl)-1,2,3-thiadiazole-4- carboxamide::US12590087, Compound 15

SMILES O=C(Nc1snnc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cncc(C(F)(F)F)c1

InChI Key InChIKey=IRNDTFWPBFMEMU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801070   

TargetUbiquitin carboxyl-terminal hydrolase 36(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 801070BDBM801070(5-(5-(trifluoromethyl)nicotinamido)-N-(3- (trifluo...)
Affinity DataIC50: 749nMAssay Description:USP36 enzymatic assays were performed in a final volume of 6 μL in buffer containing 20 mM Tris-HCl pH 8.0, (Corning 46-031-CM), 3 mM 2-Mercaptoethan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
US Patent