BDBM801071 (R)-N-(1-(4-chlorophenyl)-2-(pyrrolidin-1- yl)ethyl)-5-(5- (trifluoromethyl)nicotinamido)-1,2,3- thiadiazole-4-carboxamide::US12590087, Compound 16

SMILES O=C(Nc1snnc1C(=O)N[C@@H](CN1CCCC1)c1ccc(Cl)cc1)c1cncc(C(F)(F)F)c1

InChI Key InChIKey=DUDIKZCBZRLLKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801071   

TargetUbiquitin carboxyl-terminal hydrolase 36(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 801071BDBM801071((R)-N-(1-(4-chlorophenyl)-2-(pyrrolidin-1- yl)ethy...)
Affinity DataIC50: 764nMAssay Description:USP36 enzymatic assays were performed in a final volume of 6 μL in buffer containing 20 mM Tris-HCl pH 8.0, (Corning 46-031-CM), 3 mM 2-Mercaptoethan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
US Patent