BDBM801078 N-(3-(difluoromethoxy)phenyl)-5-(5- (trifluoromethyl)nicotinamido)-1,2,3- thiadiazole-4-carboxamide::US12590087, Compound 23

SMILES O=C(Nc1snnc1C(=O)Nc1cccc(OC(F)F)c1)c1cncc(C(F)(F)F)c1

InChI Key InChIKey=JIUWEWFDCAKDAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801078   

TargetUbiquitin carboxyl-terminal hydrolase 36(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 801078BDBM801078(N-(3-(difluoromethoxy)phenyl)-5-(5- (trifluorometh...)
Affinity DataIC50: 900nMAssay Description:USP36 enzymatic assays were performed in a final volume of 6 μL in buffer containing 20 mM Tris-HCl pH 8.0, (Corning 46-031-CM), 3 mM 2-Mercaptoethan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/10/2026
Entry Details
US Patent