BDBM8016 (2S)-2-{[(2S,3S)-2-hydroxy-4-phenyl-3-(pyridin-2-ylformamido)butyl]amino}-4-methylpentanamide::(2S,5S,6R)-3-Aza-5-hydroxy-2-isobutyl-7-phenyl-6-(picolylamino)heptanoyl Amide::hydroxyethylamine-based inhibitor 6

SMILES CC(C)C[C@H](NC[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccccn1)C(N)=O

InChI Key InChIKey=KIJVXDJZFILBNC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8016   

TargetCathepsin D(Human)
Uppsala University

LigandPNGBDBM8016((2S,5S,6R)-3-Aza-5-hydroxy-2-isobutyl-7-phenyl-6-(...)
Affinity DataKi: >2.00E+3nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2006
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Uppsala University

LigandPNGBDBM8016((2S,5S,6R)-3-Aza-5-hydroxy-2-isobutyl-7-phenyl-6-(...)
Affinity DataKi: >2.00E+3nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2006
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
Uppsala University

LigandPNGBDBM8016((2S,5S,6R)-3-Aza-5-hydroxy-2-isobutyl-7-phenyl-6-(...)
Affinity DataKi: >2.00E+3nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2006
Entry Details Article
PubMed