BDBM801660 4-(1-((4-Methoxyphenyl)sulfonyl)-2,3-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)benzonitrile::US20260092074, Compound C3

SMILES COc1ccc(S(=O)(=O)N2CCc3c(-c4ccc(C#N)cc4)cncc32)cc1

InChI Key InChIKey=ZVPZCAPUWLFHIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 801660   

TargetCytochrome P450 11B2, mitochondrial(Human)
Guangzhou Vinnocent Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 801660BDBM801660(4-(1-((4-Methoxyphenyl)sulfonyl)-2,3-dihydro-1H-py...)
Affinity DataIC50: 0.160nMAssay Description:Genes of human CYP11B2 and rat NADPH-P450 reductase were transfected into hamster V79 cells using a lentivirus vector, and stably-expressing cell lin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/12/2026
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Guangzhou Vinnocent Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 801660BDBM801660(4-(1-((4-Methoxyphenyl)sulfonyl)-2,3-dihydro-1H-py...)
Affinity DataIC50: 0.200nMAssay Description:Genes of human CYP11B1 and rat NADPH-P450 reductase were transfected into hamster V79 cells using a lentivirus vector, and stably-expressing cell lin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/12/2026
Entry Details
US Patent