BDBM802310 (S)-6-(4'-amino-3'-fluoro-4'H,6'H- spiro[piperidine-4,5'- pyrrolo[1,2-b]pyrazol]-1-yl)-3- (2,3-dichlorophenyl)-2- methylpyrimidin-4(3H)-one::US20260109699, Example 1

SMILES Cc1nc(N2CCC3(CC2)Cn2ncc(F)c2[C@H]3N)cc(=O)n1-c1cccc(Cl)c1Cl

InChI Key InChIKey=FJVYCBRGNVWOPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802310   

LigandChemical structure of BindingDB Monomer ID 802310BDBM802310((S)-6-(4'-amino-3'-fluoro-4'H,6'H- spiro[piperidin...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent