BDBM8075 2-anilino-4-(1H-pyrrol-3-yl) pyrimidine deriv. 8f::4-{2-[(3-hydroxy-4-methylphenyl)amino]pyrimidin-4-yl}-3,5-dimethyl-1H-pyrrole-2-carbonitrile

SMILES Cc1[nH]c(C#N)c(C)c1-c1ccnc(Nc2ccc(C)c(O)c2)n1

InChI Key InChIKey=HYMYXKKKNFGXRB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8075   

LigandPNGBDBM8075(4-{2-[(3-hydroxy-4-methylphenyl)amino]pyrimidin-4-...)
Affinity DataKi:  130nM ΔG°:  -9.54kcal/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2006
Entry Details Article
PubMed
LigandPNGBDBM8075(4-{2-[(3-hydroxy-4-methylphenyl)amino]pyrimidin-4-...)
Affinity DataKi:  220nM ΔG°:  -9.23kcal/moleT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2006
Entry Details Article
PubMed