BDBM8079 2-anilino-4-(1H-pyrrol-3-yl) pyrimidine deriv. 8j::4-(2,4-dimethyl-5-nitro-1H-pyrrol-3-yl)-N-(4-fluorophenyl)pyrimidin-2-amine

SMILES Cc1[nH]c(c(C)c1-c1ccnc(Nc2ccc(F)cc2)n1)N(=O)=O

InChI Key InChIKey=IJIHKBKIAXXWCC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8079   

LigandPNGBDBM8079(4-(2,4-dimethyl-5-nitro-1H-pyrrol-3-yl)-N-(4-fluor...)
Affinity DataKi:  30nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2006
Entry Details Article
PubMed
LigandPNGBDBM8079(4-(2,4-dimethyl-5-nitro-1H-pyrrol-3-yl)-N-(4-fluor...)
Affinity DataKi:  120nM ΔG°:  -9.59kcal/moleT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2006
Entry Details Article
PubMed