BDBM809318 (S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(methylthio)phenoxy)-1H-pyrazole-4-carboxamido)ethyl)benzoic Acid::US12643889, Compound I-30

SMILES CSc1cccc(Oc2c(C(=O)N[C@@H](C)c3ccc(C(=O)O)cc3)c(C(F)F)nn2C)c1

InChI Key InChIKey=MQUXALQIJXCUBM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 809318   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 809318BDBM809318((S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(methyl...)
Affinity DataKi:  6.60nMAssay Description:The bindings, to the radioligand EP4, of a control compound and the compounds prepared by Examples 1 to 43 were tested using recombinant human EP4 re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandChemical structure of BindingDB Monomer ID 809318BDBM809318((S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(methyl...)
Affinity DataIC50: 12nMAssay Description:The bindings, to the radioligand EP4, of a control compound and the compounds prepared by Examples 1 to 43 were tested using recombinant human EP4 re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent