BDBM81555 MgrA inhibitor, 4

SMILES Cc1ccc(C)n1[C@@H](CC(O)=O)c1ccsc1

InChI Key InChIKey=YJAWOHTVPDBMKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 81555   

TargetHTH-type transcriptional regulator MgrA(Staphylococcus aureus)
The University of Chicago

LigandPNGBDBM81555(MgrA inhibitor, 4)
Affinity DataIC50: 3.20E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence anisotropy (FA)-based biochemical assay that monitors MgrA-DNA binding. To determine the binding affinity of MgrA to the labeled DNA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2011
Entry Details Article
PubMed
TargetHTH-type transcriptional regulator MgrA(Staphylococcus aureus)
The University of Chicago

LigandPNGBDBM81555(MgrA inhibitor, 4)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of Staphylococcus aureus Newman His6-tagged MgrA expressed in Escherichia coli BL21(DE3) using 5'-6-F-TAAACAACAAGTTGTCCAAA-3' as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed