BDBM83349 1-(2,4-dimethyl-6-pyrazol-1-yl-benzyl)-4-(tetrahydropyran-2-ylmethyl)isonipecotic acid ethyl ester::1-[[2,4-dimethyl-6-(1-pyrazolyl)phenyl]methyl]-4-(2-oxanylmethyl)-4-piperidinecarboxylic acid ethyl ester::MLS000732853::SMR000316149::cid_16190489::ethyl 1-[(2,4-dimethyl-6-pyrazol-1-yl-phenyl)methyl]-4-(oxan-2-ylmethyl)piperidine-4-carboxylate::ethyl 1-[(2,4-dimethyl-6-pyrazol-1-ylphenyl)methyl]-4-(oxan-2-ylmethyl)piperidine-4-carboxylate::ethyl 1-[2,4-dimethyl-6-(1H-pyrazol-1-yl)benzyl]-4-(tetrahydro-2H-pyran-2-ylmethyl)piperidine-4-carboxylate

SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2cc3c(nc21)CCN3

InChI Key InChIKey=YTGGZTZJNBIMGR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 83349   

TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 83349BDBM83349(US20250388583, Compound 608)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent