BDBM8397 4-{[3-(4-bromophenyl)-1H-pyrazol-5-yl]amino}benzene-1-sulfonamide::Anilinopyrazole deriv. 1c

SMILES NS(=O)(=O)c1ccc(Nc2cc(n[nH]2)-c2ccc(Br)cc2)cc1

InChI Key InChIKey=OMCNPZUKTXGTFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8397   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8397(4-{[3-(4-bromophenyl)-1H-pyrazol-5-yl]amino}benzen...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
LigandPNGBDBM8397(4-{[3-(4-bromophenyl)-1H-pyrazol-5-yl]amino}benzen...)
Affinity DataIC50: 126nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed