BDBM8403 1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-(3-{5-[(4-sulfamoylphenyl)amino]-1H-pyrazol-3-yl}phenyl)urea::Anilinopyrazole deriv. 1n

SMILES NS(=O)(=O)c1ccc(Nc2cc(n[nH]2)-c2cccc(NC(=O)Nc3cc(ccc3F)C(F)(F)F)c2)cc1

InChI Key InChIKey=RSDHVIKBVVEOQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8403   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM8403(1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-(3-{5-[(4...)
Affinity DataIC50: 61.6nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed
LigandPNGBDBM8403(1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-(3-{5-[(4...)
Affinity DataIC50: 794nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2006
Entry Details Article
PubMed