BDBM8459 2-[(5Z)-4-oxo-2-sulfanylidene-5-{[5-(thiophen-2-yl)thiophen-2-yl]methylidene}-1,3-thiazolidin-3-yl]acetic acid::ChemBiolDrugDes71131 Compound 66::Rhodanine-thiophene analogue 24

SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(s2)-c2cccs2)C1=O

InChI Key InChIKey=PZQSQUMQKAMMNA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8459   

TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8459(ChemBiolDrugDes71131 Compound 66 | 2-[(5Z)-4-oxo-2...)
Affinity DataIC50: 2.30E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2006
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandPNGBDBM8459(ChemBiolDrugDes71131 Compound 66 | 2-[(5Z)-4-oxo-2...)
Affinity DataIC50: 2.30E+3nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed