BDBM86115 LDHA Inhibitor, 9

SMILES O=c1[nH]n(-c2ccccc2)c2ncccc12

InChI Key InChIKey=LQAKRSXPUIKTEV-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 86115   

TargetL-lactate dehydrogenase A chain(Rat)
Astrazeneca

LigandPNGBDBM86115(LDHA Inhibitor, 9)
Affinity DataKd:  3.00E+5nMpH: 7.5Assay Description:NMR spectra were acquired on Bruker Avance 600 MHz spectrometers at 298 K using a 5 mm triple-resonance HCN cryoprobe. Ligand binding was detected u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Rat)
Astrazeneca

LigandPNGBDBM86115(LDHA Inhibitor, 9)
Affinity DataKd:  1.60E+6nMpH: 7.4Assay Description:A BIAcore 3000 or a BIAcore S51 instrument (GE Healthcare) was used to detect binding interactions using a direct binding assay format.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed
TargetL-lactate dehydrogenase A chain(Rat)
Astrazeneca

LigandPNGBDBM86115(LDHA Inhibitor, 9)
Affinity DataIC50: 5.00E+5nMpH: 7.5 T: 2°CAssay Description:Enzyme assay using lactate dehydrogenase A (LDHA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2012
Entry Details Article
PubMed