BDBM8664 4-[(1E)-(2-{1-[3-(trifluoromethoxy)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl}hydrazin-1-ylidene)methyl]pyridine::pyrazolopyrimidine derivative 16

SMILES FC(F)(F)Oc1cccc(c1)-n1ncc2c(N=NCc3ccncc3)ncnc12

InChI Key InChIKey=PSUMBGPAZYSXSK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8664   

TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8664(4-[(1E)-(2-{1-[3-(trifluoromethoxy)phenyl]-1H-pyra...)
Affinity DataIC50: 316nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed