BDBM86654 Bicyclic hydroxy-1H-pyrrolopyridine-trione, 1

SMILES Cc1nnc(o1)C(=O)C(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C

InChI Key InChIKey=ROCQGNQMSKNGJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 86654   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM86654(Bicyclic hydroxy-1H-pyrrolopyridine-trione, 1)
Affinity DataIC50: 67nMAssay Description:The compound were evaluated in biochemical IN (integrase) assay that measure inhibitory potency (IC50 values)against both the 3'-processing(3'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed