BDBM8668 N-(3-{4-[(2E)-2-(pyridin-4-ylmethylidene)hydrazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)butanamide::pyrazolopyrimidine derivative 20

SMILES CCCC(=O)Nc1cccc(c1)-n1ncc2c(N=NCc3ccncc3)ncnc12

InChI Key InChIKey=VJQVFCXGKQTQLM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8668   

TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

LigandPNGBDBM8668(N-(3-{4-[(2E)-2-(pyridin-4-ylmethylidene)hydrazin-...)
Affinity DataIC50: 631nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-33P] ATP. Af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed